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Symbol PSTX
Name Poseida Therapeutics, Inc.
Currency USD
Sector Health Care
IndustryGroup Pharmaceuticals, Biotechnology & Life Sciences
Industry Biotechnology
Market NASDAQ Global Select
Country United States
State CA
City San Diego
Zipcode 92121
Website http://www.poseida.com
Roche's decision to acquire Poseida Therapeutics for $1 billion upfront came after initial reluctance, as filings reveal that partner Astellas did not submit an offer. Prior to Roche's announcement, another undisclosed pharmaceutical company had expressed interest in Poseida's cell therapy assets.
Roche has initiated a tender offer for all outstanding common shares of Poseida Therapeutics at nine dollars per share in cash, along with a contingent value right (CVR) for potential additional payments of up to four dollars per share. The offer will expire on January 7, pending regulatory approvals and the valid tender of a majority of shares.
Roche has initiated a tender offer for all outstanding shares of Poseida Therapeutics at $9.00 per share in cash, along with a contingent value right for potential additional payments of up to $4.00 per share. This offer follows a merger agreement dated November 25, 2024, and will expire on January 7, 2025, unless extended. Roche has filed the necessary documentation with the United States Securities and Exchange Commission.
Roche plans to acquire Poseida Therapeutics for $1.5 billion, focusing on allogeneic CAR-T cell therapies, including the investigational dual CAR-T therapy P-CD19CD20-ALLO1, currently in phase 1 trials for B-cell malignancies. The acquisition aims to enhance development in oncology, immunology, and neurology, with potential applications for multiple sclerosis and systemic lupus erythematosus. The deal is expected to close in Q1 2025.
Roche's subcutaneous Lunsumio has shown comparable efficacy to its intravenous version in treating follicular lymphoma, with an overall response rate of 76.6% versus 81.1% for IV. The new formulation offers advantages in administration time and safety, with lower rates of adverse events and cytokine release syndrome. Roche is also advancing its bispecific therapies, including trials for Lunsumio in combination with other treatments for diffuse large B-cell lymphoma.

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